Becker’s Muscular Dystrophy (BMD)
Becker’s Muscular Dystrophy (BMD) refers to a genetic (X-linked recessive disorder) involving dystrophin gene mutation, which results in progressive muscle degeneration most often in the proximal lower limbs but sometimes complicated by heart failure1.
Epidemiology
Onset
Varies widely between 5-60years1
Etiology
Pathophysiology
DDX
Becker’s Vs Duchenne
Currently, BMD is considered a mild form of DMD rather than a separate clinical entity.
Ambulation
DMD patients are wheelchair-dependent before age 13, whereas individuals with BMD can be ambulatory even after age 161.
Treatment
Interventional trials are more rarely conducted for BMD than DMD, thus it may be useful to research treatment as well.
References
1.
Thada PK, Bhandari J, Forshaw KC, Umapathi KK. Becker Muscular Dystrophy. In: StatPearls. StatPearls Publishing; 2024. Accessed March 18, 2024. http://www.ncbi.nlm.nih.gov/books/NBK556092/
Citation
For attribution, please cite this work as:
Yomogida N, Kerstein C. Becker’s Muscular
Dystrophy (BMD). https://yomokerst.com/The
Archive/Pathologies/Muscle
Pathologies/beckers_muscular_dystrophy.html