Sedimentation Sign (SedSign)

Authors
Affiliations

Doctor of Physical Therapy

B.S. in Kinesiology

Doctor of Physical Therapy

B.A. in Neuroscience

Psychometrics

Caution

“However, some studies [1416] demonstrated that the SedSign had low sensitivity in the differential diagnosis of LSS versus non-specific low back pain (LBP)”1

SedSign Psychometrics
Severity Sensitivity Specificity +LR -LR
Severe 0.95 (85.5, 99.6)1 4.7 (0.4–13.2)1 1.002 1.082
Moderate 0.742 (0.569, 0.883)1 0.226 (0.094, 0.394)1 0.961 1.141
Mild 0.588 (0.416, 0.76)1 0.610 (0.456, 0.764)1 1.511 0.681
Normal Individuals N/A 0.80 (0.715, 0.873)1 N/A N/A

References

1.
Zhang L, Chen R, Liu B, Zhang W, Zhu Y, Rong L. The nerve root sedimentation sign for differential diagnosis of lumbar spinal stenosis: A retrospective, consecutive cohort study. European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2017;26(10):2512-2519. doi:10.1007/s00586-016-4435-2
2.
Zhang P, Dong B, Yuan P, Li X. Human umbilical cord mesenchymal stem cells promoting knee joint chondrogenesis for the treatment of knee osteoarthritis: A systematic review. Journal of Orthopaedic Surgery and Research. 2023;18(1):639. doi:10.1186/s13018-023-04131-7

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