Seed oil debate

Authors
Affiliations

Nate Yomogida, B.S., SPT

Doctor of Physical Therapy

B.S. in Kinesiology

Chloë Kerstein, B.S., SPT

Doctor of Physical Therapy

B.A. in Neuroscience

youtube-nutrition made simple

Flaxseed oil

Dr. Carvalho cited an SR/Meta analysis by Ren et al.1, which included 8 articles about flaxseed oil and its relation to the C-reactive protein, an inflammatory marker. Ren et al.1 concluded that Flaxseed oil has no significant CRP lowering effect1.

Out of the 8 studies, only two compared flaxseed oil (experimental) to olive oil (control), the other studies compared flaxseed oil to other Omega-6 oils such as safflower, sunflower oil, or soybean oil.

Study Experimental Control Dosage
Foster 20132 Flaxseed oil Olive oil 2000mg (0.)

Foster 2013

  • Participants
    • n=43
    • Women
    • Type 2 DM
  • Design
    • Randomized
    • double blind
    • Placebo controlled
  • Intervention
    • Zn supplement
    • Flaxseed oil (2000mg/day oil)
      • this was chosen to achieve 1200mg/day of α-linolenic acid (a form of omega-3)
  • Control:
    • Olive oil (chosen as the placebo due to its low content of ALA)

Are Seed Oils Anti-Inflammatory?

For

Against

Importane of Omega-6 Content

Do Seed Oils Lower Heart Disease Risk?

Is It Just Ultra-Processed Foods?

Does Replacing Seed Oils with Butter Make Things Worse?

The Bigger Picture – What Does the Evidence Really Say?

1.
Ren GY, Chen CY, Chen GC, et al. Effect of Flaxseed Intervention on Inflammatory Marker C-Reactive Protein: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2016;8(3):136. doi:10.3390/nu8030136
2.
Foster M, Petocz P, Samman S. Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus. The Journal of Nutritional Biochemistry. 2013;24(9):1655-1661. doi:10.1016/j.jnutbio.2013.02.006

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