Lion’s Mane Mushroom (Hericium erinaceus)

Authors
Affiliations

Doctor of Physical Therapy

B.S. in Kinesiology

Doctor of Physical Therapy

B.A. in Neuroscience

Hericium erinaceus commonly known as “Lion’s Mane,” is an edible mushroom1

Scientific Classification

Type Lion’s Mane
Family Hericiaceae1
Order Russulales1
Class Agaricomycete1
Phylum Basidiomycota1

Medicinal properties

  • Antioxidant1
  • Antimicrobial1
  • Anticancer effects1

Neuroprotective Properties

Neuroregenerative Properties

Mechanism

“These are likely underpinned by the numerous bioactive components identified within the mycelia and fruiting bodies of H. erinaceus, including polysaccharides, phenolic acids and terpenoids, specifically hericenones and erinacines [6,9]. Interestingly, both hericenones and erinacines can easily cross the blood–brain barrier [10]; promote nerve growth factor synthesis and secretion [11,12]; and, in animal models, have been shown to exert anti-neuroinflammatory and neuroprotective properties and promising cognition-enhancing effects”1

“Additionally, an increase in circulating pro-brain-derived neurotrophic factor (BDNF) has been observed following hericene A (isolated from H. erinaceus) administration in mice [18].”1

References

1.
Docherty S, Doughty FL, Smith EF. The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients. 2023;15(22):4842. doi:10.3390/nu15224842

Citation

For attribution, please cite this work as:
Yomogida N, Kerstein C. Lion’s Mane Mushroom (*Hericium erinaceus*). https://yomokerst.com/The Archive/Interventions/Supplementation/lions_mane_supplementation.html